Blu, Jewel and their family are living the perfect domesticated life in the city. When Jewel decides the kids need to learn to live like real birds, she insists the family venture to the Amazon. Upon their arrival, Blu and Jewel meet the locals, including Eduardo, a larger than life patriarch with a firm set of rules, who becomes a comedic obstacle for Blu; Mimi, Eduardo's warm and sassy sister, who likes to speak her mind, even to her overbearing brother; and Roberto, a perfect specimen of a wild bird who charms everyone around him and makes Blu self-conscious. As Blu tries to fit in, he worries he may lose Jewel and the kids to the call of the wild. Meanwhile, the treacherous cockatoo Nigel plots his revenge on Blu, aided by Gabi, a cute poisonous frog who is fiercely loyal to Nigel and though small in stature, possesses a huge villainous heart.