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It's been a decade since the events at Raccoon City, and the President of the United States has decided it's time to reveal the truth behind what happened. His hope is that it will calm the resurgent tide of bioterrorist activity, but when the venue where the President is located is central to a bioterrorist attack, he is transformed beyond recognition. His personal friend and Raccoon City survivor, Leon S. Kennedy, is forced to face the changed President and make the hardest decision of his life. At the same time, Bioterrorism Security Assessment Alliance member Chris Redfield arrives in China and finds the nation under threat of a similar bioterrorist attack. With no country safe from harm and the subsequent outbreaks, the entire world has one thing in common: fear that there is no hope left.